HRID480454

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)(C)[Si](C)(C)Oc1ccc2cc(Br)ccc2c1

HCID13473083

[(6-Bromonaphthalen-2-yl)oxy](tert-butyl)dimethylsilane

C16H21BrOSi

结构：CC(C)CC(=O)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1

HCID18769009

未命名化合物

PRODUCTS

生成物

结构：CC(C)CC(O)(c1ccc2cc(O[Si](C)(C)C(C)(C)C)ccc2c1)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1

HCID18769027

未命名化合物

收率 77.9%

PROCEDURE

实验过程

6-Bromo-2-tert-butyldimethylsilyloxynaphthalene (33.7 g) and 3-methyl-1-(1-trityl-1H-imidazol-4-yl)-1-butanone (31.5 g) were used as the starting materials. By the same procedure described in Reference example 1, the titled compound (40.6 g) was obtained as a colorless powder.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-b750939c237b4f36864de2cbd129d7aa
来源数据集: uspto-grants-2003_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06649643B1
来源说明: uspto-grants-2003_11

反应 SMILES

Br[C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[CH:8]=[C:7]([O:12][Si:13]([C:16]([CH3:19])([CH3:18])[CH3:17])([CH3:15])[CH3:14])[CH:6]=[CH:5]2.[CH3:20][CH:21]([CH3:49])[CH2:22][C:23]([C:25]1[N:26]=[CH:27][N:28]([C:30]([C:43]2[CH:48]=[CH:47][CH:46]=[CH:45][CH:44]=2)([C:37]2[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=2)[C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)[CH:29]=1)=[O:24]>>[Si:13]([O:12][C:7]1[CH:8]=[C:9]2[C:4](=[CH:5][CH:6]=1)[CH:3]=[C:2]([C:23]([C:25]1[N:26]=[CH:27][N:28]([C:30]([C:43]3[CH:48]=[CH:47][CH:46]=[CH:45][CH:44]=3)([C:37]3[CH:38]=[CH:39][CH:40]=[CH:41][CH:42]=3)[C:31]3[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=3)[CH:29]=1)([OH:24])[CH2:22][CH:21]([CH3:49])[CH3:20])[CH:11]=[CH:10]2)([C:16]([CH3:19])([CH3:18])[CH3:17])([CH3:15])[CH3:14]