HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cycloheptylamine → HCID 178450073, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cycloheptylamine | HCID 2899 | — |
| Reactant | 6-(1-hydroxy-2-methyl-1-(1-trityl-1H-imidazol-4-yl)propyl)-2-naphthoic acid | HCID 18769101 | — |
| Reactant | methyl 6-(1-hydroxy-2-methyl-1-(1-trityl-1H-imidazol-4-yl)propyl)-2-naphthoate | HCID 22285069 | — |
| Product | HCID 178450073 | HCID 178450073 | — |
Reaction Steps
In a manner to that described in Example 9-(i), methyl 6-(1-hydroxy-2-methyl-1-(1-trityl-1H-imidazol-4-yl)propyl)-2-naphthoate (490 mg) was converted to 6-(1-hydroxy-2-methyl-1-(1-trityl-1H-imidazol-4-yl)propyl)-2-naphthoic acid, which was reacted with cycloheptylamine (0.20 mL) in a similar manner as described in Example 24-(i) to give the titled compound (560 mg) as a colorless powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06649643B1 |
| Source dataset | uspto-grants-2003_11 |
| ORD ID | ord-db255ca696c74fb98d2bdcbc16cd43d9 |
| Source note | uspto-grants-2003_11 |