HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 69985920, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Dichloromethane methanol | HCID 21226129 | — |
| Reactant | HCID 66616904 | HCID 66616904 | — |
| Product | HCID 69985920 | HCID 69985920 | — |
Reaction Steps
Obtained by treating a methanolic solution of 4-[(3-chloro-4-fluorophenyl)amino]-6-{[4-((R)-6-methyl-2-oxomorpholin-4-yl)-1-oxo-2-buten-1-yl]amino}-7-cyclopropylmethoxyquinazoline with ethereal hydrochloric acid at room temperature. Rf value: 0.37 (silica gel, methylene chloride/methanol=20:1); mass spectrum (ESI−): m/z=570, 572 [M−H]−.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06653305B2 |
| Source dataset | uspto-grants-2003_11 |
| ORD ID | ord-3e72cd31c9e64d6aad0111d5275c1a91 |
| Source note | uspto-grants-2003_11 |