HCID 131724221, compound → HCID 18765895, compound

Participants

Reaction Steps

A mixture of ethyl (2E)-3-(2-{[2-(1-pyrrolidinyl)ethoxy]methyl}phenyl)-2-propenoate (8.27 g, 27.3 mmol) and 5% Pd/C (800 mg) in ethanol (50 ml) was hydrogenated under a hydrogen balloon for 3 h The reaction mixture was filtered through a pad of celite and the resulting Pd/C on the celite pad was washed with ethanol. The filtrate was evaporated in vacuo to afford the titled compound (8.10 g, 97.2%) as a yellow oil.

Provenance & Evidence