HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphenylphosphine → (6-Benzyloxynaphthalen-2-ylmethyl)-triphenyl-phosphonium Bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | 2-Benzyloxy-6-bromomethyl-naphthalen | HCID 21976917 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | (6-Benzyloxynaphthalen-2-ylmethyl)-triphenyl-phosphonium Bromide | HCID 20632177 | 98% |
Reaction Steps
The solution of 2-benzyloxy-6-bromomethyl-naphthalen (18) (1 equi.), and triphenylphosphine (1.1 equi.) in DMF (0.6 mL/mmole was stirred at 95 C for 15 h, cooled to room temperature, and quenched with ethyl acetate. The resulting white solid of (6-benzyloxynaphthalen-2-ylmethyl)-triphenylphosphonium bromide (19) was filtered and washed with ethyl acetate. Yield 98%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06703082B1 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-20e0aff8f86642d8a7a609f7ea37c173 |
| Source note | uspto-grants-2004_03 |