Hydroxyamine hydrochloride → HCID 18767232, compound

Participants

Reaction Steps

The synthesis was carried out up to the third stage according to Example 1. 2-benzyl-3-dimethylamino-1-(3-methoxyphenyl)-propan-1-one hydrochloride was then converted with hydroxylamine hydrochloride to the corresponding oxime. For this purpose 5 g (0.015 mole) of 2-benzyl-3-dimethylamino-1-(3-methoxyphenyl)-propan-1-one with 2.1 g (0.03 mole) of hydroxylamine hydrochloride were dissolved in 15 ml of water and 20 ml of ethanol. The reaction time was 5 minutes and the yield of oxime was 1.7 g (33%).

Provenance & Evidence