Methanesulfonyl chloride → HCID 54370869, compound

HRID 48135Notes

Reaction equation

HRID 48135 reaction equation
[OH:1][N:2]=[C:3]([C:6](=[O:15])[CH:7]=[CH:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:4]#[N:5].[CH3:16][S:17](Cl)(=[O:19])=[O:18]>C(N(CC)CC)C>[CH3:16][S:17]([O:1][N:2]=[C:3]([C:6](=[O:15])[CH:7]=[CH:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:4]#[N:5])(=[O:19])=[O:18]

Participants

4

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 853529192-Hydroxyimino-3-oxo-5-phenyl-pent-4-enenitrile

Product 1

HCID 54370869HCID 54370869, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

2-Hydroxyimino-3-oxo-5-phenyl-pent-4-enenitrile (4.0 g; 0.02 mol) is treated with methanesulfonyl chloride and triethylamine as described in example 3.4. The crude brown product is recrystallized from 40 ml of ethanol. 2-Methylsulfonyloxyimino-3-oxo-5-phenyl-pent-4-enenitrile (2.2 g; %) is obtained as a light ochre solid (mp 163-165° C.).

Workup

  1. customThe crude brown product is recrystallized from 40 ml of ethanol

Sources & evidence

ORD record
ord-8b9d722b78724b20addbd43847a3f651
Source dataset
uspto-grants-2004_03
Patent number
US06703182B1

Reaction notes

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