HuagongsheHuagongshe Chemistry Print Report · For research reference only
8-Amino-2-naphthalenol → 8-(4-Methylpiperazin-1-yl)naphthalen-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8-Amino-2-naphthalenol | HCID 8358 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 3-(4-Methylpiperazin-1-yl)phenol | HCID 11011455 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | 8-(4-Methylpiperazin-1-yl)naphthalen-2-ol | HCID 10800217 | 48% |
Reaction Steps
Compound 16A is prepared according to the same procedure as 13A, using the following reactants: 8-aminonaphthalen-2-ol (1.6 g, 10 mmol) 2-chloro-N-(2-chloroethyl)-N-methylethanamine hydrochloride (2 g, 10.4 mmol), sodium carbonate (0.54 g, 5 mmol), 1-butanol (20 ml).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05789412 |
| Source dataset | uspto-grants-1998_08 |
| ORD ID | ord-b9d3068031634f1f82632db11da505a4 |
| Source note | uspto-grants-1998_08 |