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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 481392Generated: October 27, 2026

5,7-Dimethyl-2-propyl-1H-imidazo[4,5-b]pyridine → 1-[5-(5,7-Dimethyl-2-propylimidazo[4,5-b]pyridin-3-ylmethyl)thiophen-2-yl]cyclopent-3-ene carboxylic acid ethyl ester

https://huagongshe.com/reaction/481392

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5,7-Dimethyl-2-propyl-1H-imidazo[4,5-b]pyridineHCID 15076142—
Reactant1-(5-Chloromethylthiophen-2-yl)-cyclopent-3-ene carboxylic acid ethyl esterHCID 54533137—
Product1-[5-(5,7-Dimethyl-2-propylimidazo[4,5-b]pyridin-3-ylmethyl)thiophen-2-yl]cyclopent-3-ene carboxylic acid ethyl esterHCID 70086605—

Reaction Steps

Alkylation was performed on (5) as described in Example 1, Step 5, above, using 2-propyl-5,7-dimethylimidazo[4,5-b]pyridine (10) to yield the title compound (9).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05789415
Source datasetuspto-grants-1998_08
ORD IDord-3002a2b489934cfbb4065b5dd036de0f
Source noteuspto-grants-1998_08