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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 481395Generated: October 30, 2026

2,6-Dimethyl-8-ethyl-1-deazapurine → 2-[5-(2-Ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-ylmethyl)thiophen-2-yl]indan-2-carboxylic acid ethyl ester

https://huagongshe.com/reaction/481395

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-Dimethyl-8-ethyl-1-deazapurineHCID 9815374—
Reactant2-(5-Chloromethylthiophen-2-yl)-indan-2-carboxylic acid ethyl esterHCID 57078924—
Product2-[5-(2-Ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-ylmethyl)thiophen-2-yl]indan-2-carboxylic acid ethyl esterHCID 86752958—

Reaction Steps

The product of Step 4, above (26), was alkylated as described in Example 1, Step 5 using 2-ethyl-5,7-dimethylimidazo[4,5-b]pyridine (7) to yield the title compound (27).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05789415
Source datasetuspto-grants-1998_08
ORD IDord-c9f7bc7332e0458bbe46181f76d86883
Source noteuspto-grants-1998_08