Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 481398Generated: October 26, 2026

Bis(2-chloroethyl) ether → Ethyl 4-(thiophen-2-yl)oxane-4-carboxylate

https://huagongshe.com/reaction/481398

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBis(2-chloroethyl) etherHCID 8115—
ReactantEthyl 2-thienylacetateHCID 93657—
ProductEthyl 4-(thiophen-2-yl)oxane-4-carboxylateHCID 53937654—

Reaction Steps

Thiophen-2-yl-acetic acid ethyl ester (1) was dialkylated as described in Example 1, Step 1, using 1-chloro-2-(2-chloroethoxy)ethane to obtain the title compound (37).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05789415
Source datasetuspto-grants-1998_08
ORD IDord-6822c66be0f844c5a2bf027dcc29386d
Source noteuspto-grants-1998_08