関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Azobisisobutyronitrile | HCID 6547 | — |
| 反応物 | N-bromobutanimide | HCID 67184 | — |
| 反応物 | (6-Methylnaphthalen-2-yl)acetic acid ethyl ester | HCID 58186771 | — |
| 溶媒 | Carbon Tetrachloride | HCID 5943 | — |
| 生成物 | (6-Bromomethylnaphthalen-2-yl)acetic acid ethyl ester | HCID 54418685 | — |
反応手順
To a solution of the product of Step 1, above (50) (3.07 mmol), in 6 ml of CCl4 was added NBS (3.07 mmol) and azobisisobutyronitrile (0.09 mmol) and the mixture was heated to 82° C. for 2 hours. The reaction was cooled to ambient temperature and filtered through celite, washing the cake thoroughly with CCl4. The organics were then concentrated to dryness to obtain the title compound (51).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05789415 |
|---|
| 出典データセット | uspto-grants-1998_08 |
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| ORD ID | ord-7c2e3c76889c447593dedd3e50b9ea2a |
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| 出典メモ | uspto-grants-1998_08 |
|---|
