HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(5-Chloromethylthiophen-2-yl)-cyclopent-3-ene carboxylic acid ethyl ester → 3-[5-(1-ethoxycarbonylcyclopent-3-enyl)thiophen-2-ylmethyl]-5-ethyl-2-propyl-3H-imidazole-4-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(5-Chloromethylthiophen-2-yl)-cyclopent-3-ene carboxylic acid ethyl ester | HCID 54533137 | — |
| Reactant | HCID 178440056 | HCID 178440056 | — |
| Product | 3-[5-(1-ethoxycarbonylcyclopent-3-enyl)thiophen-2-ylmethyl]-5-ethyl-2-propyl-3H-imidazole-4-carboxylic acid ethyl ester | HCID 70084470 | — |
Reaction Steps
Alkylation was carried out on 1-(5-chloromethylthiophen-2-yl)cyclopent-3-ene carboxylic acid ethyl ester (5) as described in Example 1, Step 5, using 5-ethyl-2-propyl-3H-imidazole-4-carboxylic acid ethyl ester (74) to obtain the title compound (73).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05789415 |
| Source dataset | uspto-grants-1998_08 |
| ORD ID | ord-f99d8e7117004bf0bbc77d3fc8fd57a0 |
| Source note | uspto-grants-1998_08 |