反应详情

Alkylation was carried out on 1-(5-bromomethylpyridin-2-yl)cyclopentane-carboxlic acid ethyl ester (45) as described in Example 1, Step 5, using 2-butyl-5-chloro-3H-imidazole-4-carboxylic acid ethyl ester (69) to produce the title compound (82).