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1-(5-Bromomethylpyridin-2-yl)cyclopentanecarboxlic acid ethyl ester → 2-butyl-3-[6-(1-ethoxycarbonylcyclopentyl)pyridin-3-ylmethyl]-5-chloro-3H-imidazole-4-carboxylic acid ethyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(5-Bromomethylpyridin-2-yl)cyclopentanecarboxlic acid ethyl ester | HCID 70103586 | — |
| 反応物 | HCID 178441690 | HCID 178441690 | — |
| 生成物 | 2-butyl-3-[6-(1-ethoxycarbonylcyclopentyl)pyridin-3-ylmethyl]-5-chloro-3H-imidazole-4-carboxylic acid ethyl ester | HCID 70089089 | — |
反応手順
Alkylation was carried out on 1-(5-bromomethylpyridin-2-yl)cyclopentane-carboxlic acid ethyl ester (45) as described in Example 1, Step 5, using 2-butyl-5-chloro-3H-imidazole-4-carboxylic acid ethyl ester (69) to produce the title compound (82).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05789415 |
| 出典データセット | uspto-grants-1998_08 |
| ORD ID | ord-ce966d1f17ca4368af99a40dedb47453 |
| 出典メモ | uspto-grants-1998_08 |