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HRID481499

反应详情

EQUATION

反应方程式

HRID 481499 的结构方程式

REACTANTS

反应物

2
结构：CO.Cl
HCID21893726

Hydrochloride methanol

CH5ClO

结构：COc1ccc(C(C)C#N)cc1CN[C@H]1CCCN[C@H]1c1ccccc1
HCID57058185

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc(C(C)C#N)cc1CN[C@H]1CCCN[C@H]1c1ccccc1.Cl.Cl
HCID70137377

未命名化合物

收率 36%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

To a solution of Compound 19 in CH2Cl2 (10 ml) was added an excess amount of 10% HCl-MeOH (6 ml). After the solvent was evaporated in vacuo, the residual solid was recrystallized from IPA to give Compound 20 (90 mg, 36%; three steps) as a colorless crystal.

WORKUP

后处理

  1. customAfter the solvent was evaporated in vacuo
  2. customthe residual solid was recrystallized from IPA