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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 481550Generated: October 30, 2026

(2S,3S)-1-tert-Butoxycarbonyl-3-(5-(1-cyano-4-oxa-cyclohexyl)-2-methoxybenzyl)amino-2-phenylpiperidine → (2S,3S)-3-(5-(1-Cyano-4-oxa-cyclohexyl)-2-methoxybenzyl)amino-2-phenylpiperidine Dihydrochloride

https://huagongshe.com/reaction/481550

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S,3S)-1-tert-Butoxycarbonyl-3-(5-(1-cyano-4-oxa-cyclohexyl)-2-methoxybenzyl)amino-2-phenylpiperidineHCID 56987765—
Reactant(2S,3S)-3-[2-Methoxy-5-[1-(1,3-dithiolan-2-yl)-1-methylethyl]benzyl]amino-2-phenylpiperidine DihydrochlorideHCID 86752974—
Product(2S,3S)-3-(5-(1-Cyano-4-oxa-cyclohexyl)-2-methoxybenzyl)amino-2-phenylpiperidine DihydrochlorideHCID 70137374—

Reaction Steps

This compound was prepared from Compound 90 in the same manner of Compound 83.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05789423
Source datasetuspto-grants-1998_08
ORD IDord-6383eae5162544c3bc915780f710d2c7
Source noteuspto-grants-1998_08