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HRID481612

反应详情

EQUATION

反应方程式

HRID 481612 的结构方程式

REACTANTS

反应物

4
结构：CO
HCID887

Methanol

CH4O

结构：O=C(O)C(=O)O
HCID971

Oxalic acid

C2H2O4

结构：c1cc(OC[C@@H]2CO2)c2cc[nH]c2c1
HCID10943254

未命名化合物

结构：COc1cc2c(cc1OC)CCNCC2
HCID12923429

7,8-Dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepine

C12H17NO2

PRODUCTS

生成物

1
结构：COc1cc2c(cc1OC)CCN(C[C@H](O)COc1cccc3[nH]ccc13)CC2.O=C(O)C(=O)O
HCID131719697

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCOC(C)=O
溶剂HCID8857

Ethyl acetate

C4H8O2

2 次

PROCEDURE

实验过程

The title compound was prepared in similar fashion from (S)-(+)-4-(oxiranylmethoxy)-1H-indole and 7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepine. The resulting free base was dissolved in ethyl acetate, and precipitated with one equivalent of oxalic acid in ethyl acetate in 48% overall yield. FDMS m/e=396 (M+ of free base). α[D]589 =-9.34 (c=0.47, methanol).