HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 21268240, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 6-trifluoromethyl-3-(piperidin-4-yl)-1H-indole | HCID 11149840 | — |
| Reactant | 4-(3-chloropropoxy)-1H-indole | HCID 11694169 | — |
| Product | HCID 21268240 | HCID 21268240 | — |
Reaction Steps
The title compound was prepared in a fashion similar to that described in Example 192 from 6-trifluoromethyl-3-(piperidin-4-yl)-1H-indole (0.60 g, 2.2 mmol), 1-chloro-3-(1H-indole-4-oxy)propane (0.65 g, 2.2 mmol) and potassium carbonate (0.46 g, 3.4 mmol). The product was isolated as a white foam. Yield 165 mg(17%). mp 92°-97° C. FDMS m/e=442 (M+ of free base).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05789402 |
| Source dataset | uspto-grants-1998_08 |
| ORD ID | ord-71a2bcfaf96c4a3a81a35c360d07c077 |
| Source note | uspto-grants-1998_08 |