反应详情

温度

20 °C

N,N-Dimethylacetamide (14.0 parts) and 2,3,5,6-tetrafluoroterephthalic acid (2.91 parts) was heated at 70° C. for 4 hours before cooling to 20° C. adding water (7 parts) and cooling to 5° C. The precipitated solid was collected by filtration and washed with cold water and dried, the aqueous filtrates were evaporated under vacuum and the resultant solids combined to give 2,3,5,6-tetrafluorobenzoic acid (98%). 1,2,4,5-tetrafluorobenzene (2%) was also formed.

1. temperaturecooling to 5° C
2. filtrationThe precipitated solid was collected by filtration
3. washwashed with cold water
4. customdried
5. customthe aqueous filtrates were evaporated under vacuum