反应详情

To a stirred solution of N-[3-[3-(4-fluorophenoxy)phenyl]cyclopent-2-enyl]-N-hydroxylamine (1.07 g; 3.75 mM) in dry THF (10 ml) was added trimethylsilyl isocyanate (0.76 g; 5.63 mM) at room temperature. After stirring for 1 hr, ethanol (10 ml) was added. Volatiles were removed, and the resulting solids were recrystallized from ethyl acetate-n-hexane to give 0.6 g (y. 28%) of the subtitle compound [G] as colorless solids.

1. customVolatiles were removed
2. customthe resulting solids were recrystallized from ethyl acetate-n-hexane