HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydrofuran → Methyl 2-(2-formyl-4-ethylphenoxy)propionate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Methyl 2-bromopropionate | HCID 95576 | — |
| Reactant | 4-Ethyl-2-hydroxybenzaldehyde | HCID 10236017 | — |
| Product | Methyl 2-(2-formyl-4-ethylphenoxy)propionate | HCID 18981013 | — |
Reaction Steps
By the method of Example 1, Step F, 32.33 grams (0.215 mole) of 4-ethylsalicylaldehyde and 35.9 grams (0.215 mole) of methyl 2-bromopropionate was reacted in the presence of 35.7 grams (0.258 mole) of potassium carbonate in 50 mL of tetrahydrofuran, yielding 49.16 grams of methyl 2-(2-formyl-4-ethylphenoxy)propionate. The NMR spectrum was consistent with the proposed spectrum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05798316 |
| Source dataset | uspto-grants-1998_08 |
| ORD ID | ord-a38643e302ce4e87917a8e37b9e017fe |
| Source note | uspto-grants-1998_08 |