反应详情

By the method of Example 1, Step F, 32.33 grams (0.215 mole) of 4-ethylsalicylaldehyde and 35.9 grams (0.215 mole) of methyl 2-bromopropionate was reacted in the presence of 35.7 grams (0.258 mole) of potassium carbonate in 50 mL of tetrahydrofuran, yielding 49.16 grams of methyl 2-(2-formyl-4-ethylphenoxy)propionate. The NMR spectrum was consistent with the proposed spectrum.