Boron tribromide → HCID 18981060, compound

Participants

Reaction Steps

By the method of Example 12, Step B, 1.0 gram (0.0033 mole) of 1-amino-3-(4-methoxyphenyl)-6-trifluoromethyl-2,4(1H,3H)-pyrimidinedione and 2.5 grams (0.01 mole) of boron tribromide were reacted in 30 mL of methylene chloride, yielding 0.95 gram of 1-amino-3-(4-hydroxyphenyl)-6-trifluoromethyl-2,4(1H,3H)-pyrimidinedione, m.p. 150°-155° C. The NMR spectrum was consistent with the proposed spectrum.

Provenance & Evidence