Sulfuric Acid → HCID 19063061, compound

HRID 482500Notes

Reaction equation

HRID 482500 reaction equation
[OH:1][C:2]1[CH:9]=[C:8]([OH:10])[CH:7]=[CH:6][C:3]=1[CH:4]=[O:5].[C:11]12(O)[CH2:20][CH:15]3[CH2:16][CH:17]([CH2:19][CH:13]([CH2:14]3)[CH2:12]1)[CH2:18]2.S(=O)(=O)(O)O>ClCCl>[OH:1][C:2]1[CH:9]=[C:8]([OH:10])[C:7]([C:11]23[CH2:20][CH:15]4[CH2:16][CH:17]([CH2:19][CH:13]([CH2:14]4)[CH2:12]2)[CH2:18]3)=[CH:6][C:3]=1[CH:4]=[O:5]

Participants

5

Reactant 3

HCID 1118Sulfuric AcidHCID 72132,4-DihydroxybenzaldehydeHCID 641521-Adamantanol

Product 1

HCID 19063061HCID 19063061, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

5 g (36.2 mmol) of 2,4-dihydroxybenzaldehyde, 5.8 g (38.1 mmol) of 1-adamantanol of 200 ml of dichloromethane were introduced into a round-bottomed flask. 2 ml of concentrated sulfuric acid were added and the mixture was stirred at room temperature for eight hours. The reaction mixture was evaporated to dryness, the residue was taken up in water, neutralized with sodium bicarbonate and extracted with ethyl ether and the extract was dried over magnesium sulfate and evaporated.

Workup

  1. customThe reaction mixture was evaporated to dryness
  2. extractionextracted with ethyl ether
  3. dry with materialthe extract was dried over magnesium sulfate
  4. customevaporated

Sources & evidence

ORD record
ord-a72d2388b6e8448a8a4f6823c91845ae
Source dataset
uspto-grants-1998_08
Patent number
US05798354

Reaction notes

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