Tert-Butylamine → HCID 54713534, compound

HRID 482578Notes

Reaction equation

HRID 482578 reaction equation
[OH:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[NH:5][C:4](=[O:12])[C:3]=1[C:13]([O:15]C)=O.[C:17]([NH2:21])([CH3:20])([CH3:19])[CH3:18]>C(O)C>[C:17]([NH:21][C:13]([C:3]1[C:4](=[O:12])[NH:5][C:6]2[C:11]([C:2]=1[OH:1])=[CH:10][CH:9]=[CH:8][CH:7]=2)=[O:15])([CH3:20])([CH3:19])[CH3:18]

Participants

4

Reactant 2

HCID 6385Tert-ButylamineHCID 54676766Methyl 4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxylate

Product 1

HCID 54713534HCID 54713534, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

8.76 g (0.04 mol) of methyl 4-hydroxy-2-oxoquinoline-3-carboxylate was stirred with 3.7 g (0.05 mol) of tert-butylamine in 60 ml of ethanol in a miniautoclave for 8 hours at 150° C. under autogenous pressure. After cooling, the crystals were removed by suction filtration, washed with ligroin and dried.

Workup

  1. temperatureAfter cooling
  2. customthe crystals were removed by suction filtration
  3. washwashed with ligroin
  4. customdried

Sources & evidence

ORD record
ord-0388de84255a4ca785b9fbf0febb5226
Source dataset
uspto-grants-1998_08
Patent number
US05798451

Reaction notes

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