HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl chloroformate → 2-(N-methyl-N-(methoxycarbonyl)amino)-4'-difluoromethoxyacetophenone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl chloroformate | HCID 6586 | — |
| Reactant | 2-Dimethylamino-4'-difluoromethoxyacetophenone | HCID 18980927 | — |
| Product | 2-(N-methyl-N-(methoxycarbonyl)amino)-4'-difluoromethoxyacetophenone | HCID 18980988 | 60.2% |
Reaction Steps
By substantially following the procedure of Example 115b using 16.8 g (73 mmole) of 2-dimethylamino-4'-difluoromethoxy-acetophenone Example 126c and 7.6 g (81 mmole) of methyl chloroformate one obtain 12 g of 2-(N-methyl-N-(methoxycarbonyl)amino)-4'-difluoromethoxyacetophenone an oil. bp 150°-190° C. at 0.7 torr.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05798311 |
| Source dataset | uspto-grants-1998_08 |
| ORD ID | ord-90da2f8471534951819adb6563093ab8 |
| Source note | uspto-grants-1998_08 |