Bromine → HCID 20244840, compound

HRID 482700Notes

Reaction equation

HRID 482700 reaction equation
[ClH:1].Cl.[NH2:3][C:4]1[S:21][C:7]2[CH2:8][CH2:9][N:10]([CH2:13][C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=3[Cl:20])[CH2:11][CH2:12][C:6]=2[CH:5]=1.[S-:22][C:23]#[N:24].[K+].BrBr>S([O-])([O-])(=O)=O.[Cu+2]>[ClH:20].[ClH:1].[NH2:24][C:23]1[S:22][C:5]2[C:6]3[CH2:12][CH2:11][N:10]([CH2:13][C:14]4[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=4[Cl:20])[CH2:9][CH2:8][C:7]=3[S:21][C:4]=2[N:3]=1

Participants

5

Reactant 3

HCID 24408BromineHCID 516872Potassium thiocyanateHCID 20244897HCID 20244897, compound

Product 1

HCID 20244840HCID 20244840, compound

Reagents, catalysts & solvents 1

HCID 24462Copper SulfateCatalyst

Procedure

This compound was prepared from 2-amino-6-(2-chlorobenzyl)-5,6,7,8-tetrahydro-4H-thieno[2,3-d]azepine dihydrochloride, potassium thiocyanate and bromine or copper sulfate as oxidizing agent analogous to Example 1.

Sources & evidence

ORD record
ord-bf371717d13448529849427e703be8f0
Source dataset
uspto-grants-1986_03
Patent number
US04575504

Reaction notes

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