Propargyl alcohol → 3-(Trifluoromethylsulfonyloxy)prop-1-yne

HRID 482861Notes

Reaction equation

HRID 482861 reaction equation
[F:1][C:2]([F:11])([F:10])[S:3]([O:6][CH2:7][CH:8]=[CH2:9])(=[O:5])=[O:4].C(O)C#C.FC(F)(F)S(OS(C(F)(F)F)(=O)=O)(=O)=O>C(Cl)(Cl)(Cl)Cl>[F:10][C:2]([F:1])([F:11])[S:3]([O:6][CH2:7][C:8]#[CH:9])(=[O:4])=[O:5]

Participants

5

Reactant 3

HCID 7859Propargyl alcoholHCID 67749Trifluoromethanesulfonic anhydrideHCID 109322232-Propen-1-yl 1,1,1-trifluoromethanesulfonate

Product 1

HCID 30848143-(Trifluoromethylsulfonyloxy)prop-1-yne

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent

Procedure

2-Propyn-1-yl trifluoromethanesulfonate was prepared in carbon tetrachloride solution and used as a dried solution in Examples 45 through 48 in the same way that 2-propen-1-yl trifluoromethanesulfonate was prepared and was used in Examples 41 through 44 starting with 2-propyn-1-ol (propargyl alcohol) and trifluoromethanesulfonic anhydride.

Workup

  1. customwas prepared

Sources & evidence

ORD record
ord-c8bbbb23ff52456885b245a5ad4ebe79
Source dataset
uspto-grants-1986_03
Patent number
US04576905

Reaction notes

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