4,5-Dichloro-3H-1,2-dithiol-3-one → HCID 20244134, compound

HRID 482884Notes

Reaction equation

HRID 482884 reaction equation
[Cl:1][C:2]1[C:3](=[O:8])[S:4][S:5][C:6]=1Cl.[CH2:9]1[C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=2[CH2:13][CH2:12][NH:11][CH2:10]1>>[Cl:1][C:2]1[C:3](=[O:8])[S:4][S:5][C:6]=1[N:11]1[CH2:10][CH2:9][C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=2[CH2:13][CH2:12]1

Participants

3

Reactant 2

HCID 145034,5-Dichloro-3H-1,2-dithiol-3-oneHCID 14002432,3,4,5-Tetrahydro-1H-benzo(d)azepine

Product 1

HCID 20244134HCID 20244134, compoundYield 45.7%

Procedure

The procedure followed is analogous to that described in Example 1, but 4,5-dichloro-1,2-dithiol-3-one (3.16 g) and 2,3,4,5-tetrahydro-1H-benz[d]azepine (2.5 g) are used as starting substances, and, after recrystallization from acetonitrile, 4-chloro-5-(2,3,4,5-tetrahydro-1H-benz[d]azepin-3-yl)-1,2-dithiol-3-one (2.3 g) is obtained in the form of an ochre powder of m.p. 141° C.

Workup

  1. customafter recrystallization from acetonitrile

Sources & evidence

ORD record
ord-95c02aa4368845a78038329e3b853008
Source dataset
uspto-grants-1986_03
Patent number
US04576954

Reaction notes

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