HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole → 4-(4-Methyl-1H-imidazol-1-yl)butan-1-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | N-(4-Bromobutyl)phthalimide | HCID 93575 | — |
| Reactant | 3-(2-methyl-1H-imidazol-1-yl)propan-1-amine | HCID 3152105 | — |
| Reactant | 3-(2-Ethyl-1H-imidazol-1-yl)-1-propanamine | HCID 6484134 | — |
| Reactant | 3-(4-Phenyl-1H-imidazol-1-yl)propan-1-amine | HCID 13588912 | — |
| Reactant | HCID 178418800 | HCID 178418800 | — |
| Product | 4-(4-Methyl-1H-imidazol-1-yl)butan-1-amine | HCID 13618116 | — |
Reaction Steps
The procedure of Example 2 was repeated using N-(4-bromobutyl)phthalimide and 4-methyl-1H-imidazole giving the desired intermediate. Preparation of 4-phenyl-1H-imidazole-1-propanamine, 2-methyl-1H-imidazole-1-propanamine and 2-ethyl-1H-imidazole-1-propanamine was accomplished by the procedure of Example 4 using the appropriate imidazole starting materials.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04576957 |
| Source dataset | uspto-grants-1986_03 |
| ORD ID | ord-041cf5eb75ec46f3a9051027e4bb4a81 |
| Source note | uspto-grants-1986_03 |