HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorophenyl isocyanate → HCID 13580008, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorophenyl isocyanate | HCID 76833 | — |
| Reactant | 4-(1H-imidazol-1-yl)butan-1-amine | HCID 4379480 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 13580008 | HCID 13580008 | — |
Reaction Steps
A solution of 2.30 g. of o-chlorophenyl isocyanate in 30 ml. of toluene was added with stirring to a solution of 2.09 g. of 1H-imidazole-1-butanamine in 20 ml. of toluene and the mixture was allowed to stir overnight and them evaporates to a crystalline residue. The crystals were dissolved in methylene chloride and purified by HPLC (silica gel column, eluted with 10% ethanol/ethyl acetate) to obtain the desired compound, mp. 87°-88° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04576957 |
| Source dataset | uspto-grants-1986_03 |
| ORD ID | ord-96b1d7cff994462ba8a25345dc491cdf |
| Source note | uspto-grants-1986_03 |