3-Methyl-5,6,7,8-tetrahydroquinoline → HCID 178501895, compound

HRID 482978Notes

Reaction equation

HRID 482978 reaction equation
[CH3:1][C:2]1[CH:3]=[N:4][C:5]2[CH2:6][CH2:7][CH2:8][CH2:9][C:10]=2[CH:11]=1.C([Li])CCC.[CH3:17][O:18][CH:19]([SiH2:22]Cl)[O:20][CH3:21]>>[CH3:17][O:18][CH:19]([SiH2:22][CH:6]1[C:5]2[N:4]=[CH:3][C:2]([CH3:1])=[CH:11][C:10]=2[CH2:9][CH2:8][CH2:7]1)[O:20][CH3:21]

Participants

4

Reactant 3

HCID 1200283-Methyl-5,6,7,8-tetrahydroquinolineHCID 122715448HCID 122715448, compoundHCID 178418339Butyllithium

Product 1

HCID 178501895HCID 178501895, compound

Procedure

The title compound was prepared in a similar manner to that described in Example 1 using 5,6,7,8-tetrahydro-3-methylquinoline (0.01 M), butyl lithium (0.01 M) and dimethoxymethylsilyl chloride (0.015 M). The sample was distilled twice using a kugelrohr apparatus to give the title compound (0.25 g) bp 110°-120° C./0.5 mm.

Workup

  1. customThe title compound was prepared in a similar manner to that
  2. distillationThe sample was distilled twice

Sources & evidence

ORD record
ord-9e1923bed15644aaae3549d03cc52259
Source dataset
uspto-grants-1986_03
Patent number
US04577022

Reaction notes

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