Hydrogen Bromide → HCID 20242613, compound

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Reaction Steps

A solution of 1-(4-chlorophenyl)-3-dimethylamino-8-methoxy-1,4-dihydroisoquinoline hydrochloride (0.9 g) in 48% aqueous hydrobromic acid (100 ml) was heated at 115°-120° C. for 2.5 h. The solution was evaporated to dryness in vacuo and recrystallised from methanol-water to afford the title compound, (0.66 g), m.p. 185°-187° C.

Provenance & Evidence