反应详情

2.8 Grams of 2-chloro-3-chloromethylquinoline was dissolved in 30 ml of acetic acid and the solution was refluxed for 2 hours. The reaction mixture was poured into water and the crystals precipitated were collected by filtration, and were recrystallized from methanol to obtain 2.1 g of 3-chloromethylcarbostyril in the form of colorless needle-like crystals.

1. temperaturethe solution was refluxed for 2 hours
2. customthe crystals precipitated
3. filtrationwere collected by filtration
4. customwere recrystallized from methanol