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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 483170Generated: October 30, 2026

Isatin → Acetylisatin

https://huagongshe.com/reaction/483170

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsatinHCID 7054—
ReactantAcetic AnhydrideHCID 7918—
ProductAcetylisatinHCID 11321—

Reaction Steps

To 60 g of isatin was added 140 ml of acetic anhydride and the mixture was refluxed for 4 hours. The reaction mixture was cooled, and the crystals precipitated were collected by filtration, and washed with ether to obtain 58 g of N-acetylisatin.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04578381
Source datasetuspto-grants-1986_03
ORD IDord-be4e48cba67446df94e5d35b87e7808b
Source noteuspto-grants-1986_03