Hydrochloric Acid → HCID 12112293, compound

HRID 483274Notes

Reaction equation

HRID 483274 reaction equation
Cl.[CH3:2]/[C:3](/[C:14]1[CH:23]=[C:22]2[C:17]([C:18]([CH3:27])([CH3:26])[CH2:19][CH2:20][C:21]2([CH3:25])[CH3:24])=[CH:16][C:15]=1[CH3:28])=[CH:4]\[C:5]1[CH:13]=[CH:12][C:8]([C:9]([OH:11])=[O:10])=[CH:7][CH:6]=1.[CH2:29](O)[CH3:30]>>[CH3:2]/[C:3](/[C:14]1[CH:23]=[C:22]2[C:17]([C:18]([CH3:27])([CH3:26])[CH2:19][CH2:20][C:21]2([CH3:25])[CH3:24])=[CH:16][C:15]=1[CH3:28])=[CH:4]\[C:5]1[CH:6]=[CH:7][C:8]([C:9]([O:11][CH2:29][CH3:30])=[O:10])=[CH:12][CH:13]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 644198587316-44-7

Product 1

HCID 12112293HCID 12112293, compound

Procedure

Gaseous hydrogen chloride was passed into a solution of 4.0 g of E-4-[2-methyl-2-(1,1,4,4,6-pentamethyl-1,2,3,4-tetrahydronaphth-7-yl)-vinyl]-benzoic acid in 300 ml of ethanol at the boiling point of the reaction mixture, until the solution was saturated. Thereafter, the mixture was kept at the boil for a further 4 hours, cooled, flushed with nitrogen and then evaporated down. The residue was digested with 30 ml of methanol, and the product was filtered off and dried. 3.6 g of ethyl E-4-[2-methyl-2-(1,1,4,4,6-pentamethyl-1,2,3,4-tetrahydronaphth-7-yl)-vinyl]-benzoate of melting point 109°-110° C. were obtained (cf. Example 1).

Workup

  1. temperaturecooled
  2. customflushed with nitrogen
  3. customevaporated down
  4. filtrationthe product was filtered off
  5. customdried

Sources & evidence

ORD record
ord-9973146e5bc84a4a8fa5db86fac42f12
Source dataset
uspto-grants-1986_03
Patent number
US04578498

Reaction notes

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