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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 483310Generated: October 30, 2026

Hydrochloric Acid → 2-fluoro-3-methylpentanoic acid

https://huagongshe.com/reaction/483310

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantSodium HydroxideHCID 14798—
ReactantEthyl 2-fluoro-3-methylpentanoateHCID 19752044—
Product2-fluoro-3-methylpentanoic acidHCID 256896—

Reaction Steps

To 8.5 g of the compound (iv) was added 1N NaOH aqueous solution, followed by stirring at room temperature for 8 hours. The solution was acidified with dilute hydrochloric acid and then extracted with ether. The extract was freed of ether by distillation. Thus there was obtained 2-fluoro-3-methylpentanoic acid (v).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05225105
Source datasetuspto-grants-1993_07
ORD IDord-3ee9725470c043b7b30ecdb68591553f
Source noteuspto-grants-1993_07