Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | Ethyl 3-(4-methylphenyl)-3-oxopropanoate | HCID 292637 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | HCID 10085313 | HCID 10085313 | — |
Reaction Steps
20.4 g of ethyl 3-p-tolyl-3-oxopropionate (Helv. Chim. Acta 57, 2205 (1974)) are dissolved in 20 ml of CCl4. A solution of 6 ml of bromine in 30 ml of CCl4 is added dropwise at -5° C. After 1 hour at -5° C., the mixture is stirred at 20° C. for 3 h and then at 60° C. for 1 h. the solvent is removed. The title compound is used further as crude product; yield 34 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05225414 |
|---|
| Source dataset | uspto-grants-1993_07 |
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| ORD ID | ord-69d0f6b394674a0c8e08738451e76b3c |
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| Source note | uspto-grants-1993_07 |
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