HuagongsheHuagongshe Chemistry Print Report · For research reference only
[4-(Propan-2-yl)phenyl]hydrazine hydrochloride → MK 886
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [4-(Propan-2-yl)phenyl]hydrazine hydrochloride | HCID 2733248 | — |
| Reactant | Methyl 5-t-butylthio-2,2-dimethyl-4-oxopentanoate | HCID 14980531 | — |
| Product | MK 886 | HCID 3651377 | — |
Reaction Steps
Following the procedure of Example 10, but using 1-(p-chlorobenzyl)-1[-(4-(i-propyl)phenyl]hydrazine hydrochloride and methyl 2,2-dimethyl-5-(t-butylthio)-4-oxopentanoate as starting materials and hydrolysis at reflux, the title compound was prepared, mp 189°-192°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05225421 |
| Source dataset | uspto-grants-1993_07 |
| ORD ID | ord-8f0d0edbf2a448a2adab397339cd278f |
| Source note | uspto-grants-1993_07 |