HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methyl-2-piperidinemethanol → N-methyl-2-piperidylmethyl N,N-dimethylaminoacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methyl-2-piperidinemethanol | HCID 89394 | — |
| Reactant | Glycine, N,N-dimethyl-, ethyl ester | HCID 118412 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N-methyl-2-piperidylmethyl N,N-dimethylaminoacetate | HCID 19753089 | — |
Reaction Steps
A mixture of 75 g of ethyl N,N-dimethylglycinate, 75 g of 1-methyl-2-piperidylmethanol and 1 g of titanium tetra(n-butoxide) was heated at 45° C. until the amount of ethanol collected indicated the reaction was complete. After cooling a small amount of water was added, the mixture was filtered, and the filtrate was distilled under reduced pressure to provide N-methyl-2-piperidylmethyl N,N-dimethylaminoacetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05225513 |
| Source dataset | uspto-grants-1993_07 |
| ORD ID | ord-d6308de8a1ec43cdb67084bf42d56e20 |
| Source note | uspto-grants-1993_07 |