Hydrochloric Acid → HCID 18957817, compound

Participants

Reaction Steps

This compound was prepared as above form ethyl 1-hexyl-4-phenyl-4-piperidinecarboxylate hydrochloride (3.54 g, 10 mmol) and ethylamine (2.25 g, 50 mmol). Reaction time 2 days. The crude product (1.0 g) was recrystallized from disopropyl ether, yielding 0.81 g with m.p. 92°-94° C. Hydrochloride m.p. 221°-223° C. (form 2% aqueous acetone).

Provenance & Evidence