Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 48391Generated: October 29, 2026

n-[2-(1-Methyl-5-{2-[(phenylmethoxy)carbonylamino]ethyl}benzimidazol-2-yl)ethyl](phenylmethoxy)carboxamide → HCID 12991239, compound

https://huagongshe.com/reaction/48391

Reaction equation

Participants

RoleNameHCIDCharge
Reactantn-[2-(1-Methyl-5-{2-[(phenylmethoxy)carbonylamino]ethyl}benzimidazol-2-yl)ethyl](phenylmethoxy)carboxamideHCID 12991238—
CatalystPalladiumHCID 23938—
ProductHCID 12991239HCID 1299123955%

Reaction Steps

N-[2-(1-Methyl-5-{2-[(phenylmethoxy)carbonylamino]ethyl}benzimidazol-2-yl)ethyl](phenylmethoxy)carboxamide (3.6 mmol) and 10% palladium on carbon (1.0 g, 62 mole %) were combined and hydrogenation was carried out in a manner analogous to the procedure described in example 6 to provide the intermediate title compound, 2-[5-(2-aminoethyl)-1-methylbenzimidazol-2-yl]ethylamine, (55%) as a colorless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06703425B2
Source datasetuspto-grants-2004_03
ORD IDord-4dcd7b15a71b4485ad8cfeb7d00dfc15
Source noteuspto-grants-2004_03