Hydrochloric Acid → HCID 67855353, compound

HRID 483970Notes

Reaction equation

HRID 483970 reaction equation
C1(N2C3([CH2:16][CH2:15][N:14]([C:17]4([CH3:35])[CH2:22][N:21]([C:23]5[CH:28]=[CH:27][C:26](F)=[CH:25][CH:24]=5)[C:20]5[CH:30]=[CH:31][C:32]([F:34])=[CH:33][C:19]=5[O:18]4)CC3)C(=O)NC2)C=CC=CC=1.Cl>>[CH3:17][O:18][C:19]1[CH:33]=[CH:32][CH:31]=[CH:30][C:20]=1[N:21]1[CH2:23][CH2:24][N:14]([C:17]2([CH3:35])[CH2:22][N:21]([C:20]3[CH:19]=[CH:33][C:32]([F:34])=[CH:31][CH:30]=3)[C:23]3[CH:24]=[CH:25][CH:26]=[CH:27][C:28]=3[O:18]2)[CH2:15][CH2:16]1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 86745424HCID 86745424, compound

Product 1

HCID 67855353HCID 67855353, compound

Procedure

2-(1-phenyl-1,3,8-triazaspiro[4,5]decan-4-one-8-yl)-methyl-4-(4-fluorophenyl)-7-fluoro-2,3-dihydro-4H-1,4-benzoxazine, m.p. 288°-292° C., as hydrochloride.

Sources & evidence

ORD record
ord-f6814de81ab6452aae98b4e43f591257
Source dataset
uspto-grants-1993_07
Patent number
US05229383

Reaction notes

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