Acetic Anhydride → HCID 53959287, compound

HRID 484071Notes

Reaction equation

HRID 484071 reaction equation
[NH2:1][C:2]1[CH:31]=[CH:30][C:5]([CH:6]=[CH:7][CH2:8][N:9]2[CH2:14][CH2:13][C:12](=[C:15]3[C:21]4[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=4[CH:19]=[CH:18][C:17]4[CH:26]=[CH:27][CH:28]=[CH:29][C:16]3=4)[CH2:11][CH2:10]2)=[CH:4][CH:3]=1.[C:32](OC(=O)C)(=[O:34])[CH3:33]>C(N(CC)CC)C>[C:32]([NH:1][C:2]1[CH:3]=[CH:4][C:5]([CH:6]=[CH:7][CH2:8][N:9]2[CH2:10][CH2:11][C:12](=[C:15]3[C:16]4[CH:29]=[CH:28][CH:27]=[CH:26][C:17]=4[CH:18]=[CH:19][C:20]4[CH:25]=[CH:24][CH:23]=[CH:22][C:21]3=4)[CH2:13][CH2:14]2)=[CH:30][CH:31]=1)(=[O:34])[CH3:33]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 53692038HCID 53692038, compound2×

Product 1

HCID 53959287HCID 53959287, compoundYield 92.3%

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

1-(4-Aminocinnamyl)-4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)piperidine (compound 5) was N-acetylated by acetic anhydride using triethyl amine as base. Yield 92.3%

Sources & evidence

ORD record
ord-bc169c7bc37c4454b9476ea8ec0c15b8
Source dataset
uspto-grants-1993_07
Patent number
US05229400

Reaction notes

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