HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 484072Generated: October 29, 2026
Nitric Acid → 1-(3-Bromopropyl)-4-nitrobenzene
https://huagongshe.com/reaction/484072
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Nitric Acid | HCID 944 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | (3-Bromopropyl)benzene | HCID 12503 | — |
| Product | 1-(3-Bromopropyl)-4-nitrobenzene | HCID 10444482 | 63.7% |
Reaction Steps
1-Bromo-3-phenylpropane (19.7 mmol) was added slowly to a solution of sulfuric acid (7.4 g) and nitric acid (5.4 g) at ambient temperature and stirred at 60° C. The residue (mixture of ortho and para) was purified by column chromatography on silica gel. Yield 63.7%
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05229400 |
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| Source dataset | uspto-grants-1993_07 |
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| ORD ID | ord-4fc31f28ff9d4a008239c8d0eff3dbdb |
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| Source note | uspto-grants-1993_07 |
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