3-(4-Pyridyl)-2-propyn-1-ol → 4-Piperidinepropanol

HRID 484075Notes

Reaction equation

HRID 484075 reaction equation

[N:1]1[CH:6]=[CH:5][C:4]([C:7]#[C:8][CH2:9][OH:10])=[CH:3][CH:2]=1>[Rh]>[NH:1]1[CH2:6][CH2:5][CH:4]([CH2:7][CH2:8][CH2:9][OH:10])[CH2:3][CH2:2]1

Participants

3

Reactant 1

HCID 121814433-(4-Pyridyl)-2-propyn-1-ol

Product 1

HCID 814974-Piperidinepropanol

Reagents, catalysts & solvents 1

HCID 23948RhodiumCatalyst

Procedure

1-(4-Pyridyl)-1-propine-3-ol was hydrogenated with rhodium on alumina as catalyst.

Sources & evidence

ORD record: ord-8fcc5179014b4c69bedaf82fe1ee221c
Source dataset: uspto-grants-1993_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05229400

Reaction notes

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