HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acrylic Acid → p-Cyanocinnamic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acrylic Acid | HCID 6581 | — |
| Reactant | Benzonitrile, 4-bromo- | HCID 12162 | — |
| Product | p-Cyanocinnamic acid | HCID 86773 | 78.6% |
Reaction Steps
A Heck reaction of 4-bromobenzonitrile and acrylic acid gave 4-cyanocinnamic acid. The acid was reduced to the corresponding alcohol with ethyl chloroformate and then sodium borohydride. Yield 78.6%
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05229400 |
| Source dataset | uspto-grants-1993_07 |
| ORD ID | ord-dc94752bce6c406a9b44b5f7de706f09 |
| Source note | uspto-grants-1993_07 |