HRID484078

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6581

Acrylic acid

C3H4O2

HCID12162

Benzonitrile, 4-bromo-

C7H4BrN

PRODUCTS

生成物

HCID86773

3-(4-Cyanophenyl)-2-propenoic acid

C10H7NO2

收率 78.6%

PROCEDURE

实验过程

A Heck reaction of 4-bromobenzonitrile and acrylic acid gave 4-cyanocinnamic acid. The acid was reduced to the corresponding alcohol with ethyl chloroformate and then sodium borohydride. Yield 78.6%