HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminoindane → 2-(2-Indanylamino)-1-thia-2,3,5,7-tetraazaindene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminoindane | HCID 76310 | — |
| Reactant | 2-Chloro-1-thia-2,3,5,7-tetraazaindene | HCID 22719619 | — |
| Product | 2-(2-Indanylamino)-1-thia-2,3,5,7-tetraazaindene | HCID 22719639 | 51.7% |
Reaction Steps
Using 2-chloro-1-thia-2,3,5,7-tetraazaindene (50 mg, 0.29 mmol) (see J. Org. Chem. 26, 4961 (1961), J. Chem. Soc. (C) 1856 (1967)) and 2-aminoindan (120 mg, 0.90 mmol), a similar procedure to Production Example 190 was carried out. The product obtained was purified by silica gel chromatography (hexane:ethyl acetate=3:1) to obtain the title compound (41 mg, 0.15 mmol) having the following physical properties:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06703421B1 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-8f80ee803ed04db89c1d79578a7d8e16 |
| Source note | uspto-grants-2004_03 |